About

I am pro-active, results orientated, thorough and highly flexible practicing epidemiologist and medical doctor with attention to detail. I have previously worked as a Research Scientist at MRC/UVRI & LSHTM Uganda Research Unit, with more more than 14 years of experience in clinical research. My experience is mainly leading successful therapeutic and vaccine trials. I am currently a co-investigator in the conduct of an observation study investigating humoral and cellular immune responses among recently infected Rift Valley Fever (RVF) survivors. I have previously participated/ or led the conduct of six therapeutic/vaccine trials including four phase 3 trials and two phase 1 and 2 trials. In 2003, I graduated with a bachelors degree of Bachelor of Medicine and Bachelor of Surgery (MBChB) at Mbarara University of Science and Technology (MUST) Uganda. In November 2007 and November 2010 I completed a post-graduate diploma in Epidemiology and a Master of Science degree in Epidemiology at University of London respectively. I have also completed research related courses of GCP, HSP, statistics and project management. My research interest include the epidemiology of infectious diseases mainly Malaria, tuberculosis and HIV and vaccinology of infectious diseases mainly haemorrhagic viruses

Skills

  • Healthcare
  • Project Management
  • Data Management
    7
  • Data Analysis
    6
  • Data Entry
    10
  • Competent research skills. Data collection
    10
  • Data analysis with SPSS and STATA
    4
  • Monitoring and Evaluation (Data Management)
    8
  • English
    9
  • Luganda
    10
  • Runyankole
    5
  • KISWAHILI
    1

Experience

Abu-Baker Ggayi

Work experience
  • November, 2020 - November, 2022
  • Fulltime
  • Study title: PROTOCOL VAC52150EBL2010: An Open Label, Phase 2 Study to Evaluate the Safety and Immunogenicity of an Ad26.ZEBOV Booster dose in Human Immunodeficiency Virus positive (HIV+) Adults Previously Vaccinated with the Ad26.ZEBOV, MVA-BN-Filo Vaccine Regimen.
  • 1. Obtained ethics and regulatory approvals within two months
  • 2. Provided overall leadership of the study team (clinical, community, data, pharmacy and Laboratory staff)
  • 3. Participated in recruitment, training (SOPs and protocol) and the day to day supervision of the study team
  • 4. Prepared and submitted annual progress reports to the sponsor, ethics and regulatory authorities and the PI in a timely manner.
  • 5. Supervised data collection, cleaning and generated periodic reports
  • 6. Prepared, submitted protocol amendment and obtained approval.
  • 7. Contributed immensely to manuscript writing (main publication).
  • 8. Drafted the study budget and managed the day to day financial expenditure.
  • 9. Maintained the Investigator site File (ISF)
  • 10. Disseminated the results to the participants, Community Advisory board, Unit scientific team and internationally to the 2022 ASTMH Conference in Seattle, USA.
  • 11. Archived the study records.
  • 12. Contributed to the main manuscript (Choi, Edward Man-Lik, et al. "Safety and immunogenicity of an Ad26. ZEBOV booster vaccine in human immunodeficiency virus positive (HIV+) adults previously vaccinated with the Ad26. ZEBOV, MVA-BN-Filo vaccine regimen against Ebola: a single-arm, open-label phase II clinical trial in Kenya and Uganda." Vaccine 41.50 (2023): 7573-7580.)

Abu-Baker Ggayi

Work experience
  • Responsibilities and achievements
  • 1.Clerked (took history) and conducted physical examinations on OPD patients and clients.
  • 2. Requested and reviewed lab and radiologic investigations
  • 3. Wrote Prescriptions and monitored adherence and response to treatment.
  • 4. Undertook emergency interventions.
  • 5. conducted Obstetric care including antenatal, supervised deliveries and post natal services.
  • 6. Handled obstetric and gynaecological emergences especially during night covers when the inhouse specialists were absent.
  • 7. Offered emergency medical and surgical services.
  • 8. Conducted medical referrals as needed
  • 9. Conducting CME sessions
  • 10. Wrote medical reports (schools, insurance and expatriate employees)

Abu-Baker Ggayi

Work experience
  • September, 2018 - February, 2025
  • Fulltime
  • Study title: Phase I Study to Determine the Safety and Immunogenicity of the Candidate Rift Valley Fever Virus (RVFV) Vaccine ChAdOx1 RVF among Healthy Adult Volunteers in Uganda.
  • Study title: Study Protocol investigating humoral and cellular immune responses among recently infected Rift Valley Fever (RVF) survivors - (RVF Survivors study)
  • Achievements
  • 1. Obtained ethics and regulatory approvals
  • 2. Maintained the Investigator site File (ISF)
  • 3. Provided overall leadership of the study team
  • 4. Participated in study staff recruitment, training (SOPs and protocol) and the day to day supervision of the study team
  • 5. Prepared and submitted annual progress reports to the sponsor, ethics and regulatory bodies and the PI in a timely manner
  • 6. I supervised quality data collection, cleaning and generated periodic reports for monitoring purposes
  • 7. Prepared and submitted protocol amendments
  • 8. Successfully disseminated study results to stakeholders, the press, the CAB and the unit scientific meeting.
  • 9. Substantial contribution to the to manuscripts writing (Anywaine, Zacchaeus, et al. "Severe morbidity and hospital-based mortality from Rift Valley fever disease between November 2017 and March 2020 among humans in Uganda." Virology Journal 21.1 (2024): 104.)
  • 10. Successfully archived the study records for the trial.
  • 11, Planned and conducted the field visits for the observation study
  • 13. Represented study staff in biweekly investigators- sponsor meetings

Abu-Baker Ggayi

Work experience
  • Study title: A Randomized, Observer-blind, Placebo-controlled, Phase 2 Study to Evaluate the Safety, Tolerability and Immunogenicity of Different Prime-boost Regimens of the Candidate Prophylactic Vaccines for Ebola Ad26.ZEBOV and MVA-BN-Filo in Healthy Adults, Including Elderly Subjects, HIV-infected Subjects, and Healthy Children in Two Age Strata in Africa
  • 1. Provided efficient leadership and coordination of different study departments.
  • 2. Planning and budgeting for different aspects of study activities.
  • 3. Participated in the development of protocols, SOPs, and data collection tools
  • 4. Conducted data quality assessments, mentorship, and CMEs of the study team.
  • 5. Ensured proper administration of informed consent, and proper collection and management of data and samples from study participants.
  • 6. Prepared and distributed study updates and reports to the sponsor, ethics and regulatory authorities.
  • 7. Led study team meetings
  • 8. Participate in data analysis, manuscripts preparation, and dissemination of study findings in collaboration with the data management team , community engagement team and the other investigators.
  • 9. Prepared, submitted and achieved ethics and regulatory approvals for the protocol and its amendments

Abu-Baker Ggayi

Work experience
  • Study title: A Phase 1 Study to Evaluate the Safety, Tolerability and Immunogenicity of Heterologous Prime-Boost Regimens Using MVA-BN®-Filo and Ad26.ZEBOV Administered in Different sequences and Schedules in Healthy Adults
  • Responsibilities
  • 1.Submitted and obtained ethics and regulatory approvals
  • 2.Maintained the Investigator site File (ISF)
  • 3. Provided overall leadership of the multi-disciplinary study team
  • 4. Actively participated in staff recruitment, training (SOPs and protocol) and the day to day supervision of the study team
  • Prepared and submitted annual progress reports to the sponsor, ethics and regulatory bodies and the PI
  • 5. Oversaw data collection, cleaning and generating periodic reports
  • 6. Contributed to manuscripts writing (both main and sub studies); (Kitonsa, Jonathan, et al. "Implementation of accelerated research: strategies for implementation as applied in a phase 1 Ad26. ZEBOV, MVA-BN-Filo two-dose Ebola vaccine clinical trial in Uganda." Global Health Action 13.1 (2020): 1829829.)
  • 7. Attended and participated in resolving dat queries from sponsor monitors
  • 8. Attended study audit, ethics and regulatory inspections
  • 9. Successfully oversaw results dissemination to the CAB, participants and stakeholders

Abu-Baker Ggayi

Work experience
  • Study title: CryptoDex: A Randomized, Double Blind, Placebo-Controlled Phase III Trial of Adjunctive Dexamethasone in HIV infected Adults with Cryptococcal Meningitis.
  • Responsibilities
  • 1.Submitted and obtained ethics and regulatory approvals
  • 2.Maintained the Investigator site File (ISF)
  • 3. Provided overall leadership of the multi-disciplinary study team
  • 4. Actively participated in staff recruitment, training (SOPs and protocol) and the day to day supervision of the study team
  • Prepared and submitted annual progress reports to the sponsor, ethics and regulatory bodies and the PI
  • 5. Oversaw data collection, cleaning and generating periodic reports
  • 6. Contributed to manuscripts writing (Beardsley, Justin, et al. "Adjunctive dexamethasone in HIV-associated cryptococcal meningitis." New England Journal of Medicine 374.6 (2016): 542-554.); (Kitonsa, Jonathan, et al. "Factors affecting mortality among HIV positive patients two years after completing recommended therapy for Cryptococcal meningitis in Uganda." PLoS One 14.1 (2019): e0210287.)
  • 7. Attended and participated in resolving data queries from sponsor monitors
  • 8. Actively participated in consent, Randomisation and clinical care of study participants
  • 9. Successfully oversaw results dissemination to the CAB, participants and stakeholders

Abu-Baker Ggayi

Work experience
  • Study title: Prospective, Observational, Multi-centre Study to evaluate laboratory, clinical, immunologic and viral markers of disease progression in recently HIV-infected volunteers (Protocol C)
  • Responsibilities:
  • 1. Responsible to getting ethics and regulatory approvals
  • 2. Overall leadership of the study team
  • 3. Responsible for recruitment, training (SOPs and protocol) and the day to day supervision of the study team
  • 4. Preparing and submitting annual progress reports to the sponsor, ethics and regulatory authorities and the PI
  • 5. Data collection, cleaning and generating periodic reports
  • 6. Preparing and submitting protocol amendments
  • 7. Contributed to a couple of manuscript writing (Price, Matt A., et al. "Control of the HIV-1 load varies by viral subtype in a large cohort of African adults with incident HIV-1 infection." The Journal of infectious diseases 220.3 (2019): 432-441; Price, Matt A., et al. "IAVI's HIV epidemiology and early infection cohort studies in Africa to support vaccine discovery." (2020): 29-30.)
  • 8. Generated budgets and managed the day to day financial expenditure.
  • 9. Maintained the Investigator site File (ISF)
  • 10. Ensured that queries from the monitors were resolved in a timely manner

Abu-Baker Ggayi

Work experience
  • In-charge Namayumba Health Centre and Busiro North Health Sub district.
  • Responsibilities:
  • 1. Coordinated curative and primary health care services in Busiro North sub-district.
  • 2. Supervised child days which included mass polio and measles vaccinations
  • 3. Conducted support supervision services of all lower health units
  • 4. Supervised preventive and curative health services at Namayumba health Centre IV
  • 5. Attended monthly district health meetings
  • 6. Conducted appraisals to heads of departments in the health Centre IV and in-charges of health centres

Abu-Baker Ggayi

Work experience
  • September, 2012 - April, 2013
  • Fulltime
  • Responsibilities
  • 1. General Medical care of outpatient and in-patients.
  • 2. Attended to Medical, surgical and obstetric /gynaecological emergencies
  • 3. Daily review of admitted patients
  • 4. Referred very sick patients to higher health facilities as needed.

Abu-Baker Ggayi

Work experience
  • Responsibilities/ Achievements:
  • 1. Provided oversight of initiation and implementation of Basic package of health services (BPHS) activities in two counties of Central Equatoria state, South Sudan which included:
  • i) Conducted a situation analysis of existing services
  • ii) Identified staffing, equipment and health infrastructural gaps
  • iii) Supervised the procurement of Motor vehicles, motor cycles, EPI and maternal equipment
  • iv) Participated in recruitment of missing essential health workers
  • v) Supervised the implementation of basic health services mainly focusing on high impact interventions like childhood immunization, maternity services (antenatal , skilled birth attendant and postnatal)- Achieved all project targets.
  • 2. Coordinated the activities of all health related implementing partners (other NGOs) through quarterly coordination meetings
  • 3 . Coordinate the monthly county health coordination meetings.
  • 4. Attended and actively participate in the quarterly state health NGOs coordination meetings
  • 5. Compiled and reported the monthly and quarterly project activities to the County Health Department , and the Lead Agency (Norwegian People's AID-(NPA))
  • 6. Supervise the Payam project assistants and the project admin/finance/logistic
  • 7. Carried out biannual project staff performance appraisal and gave appropriate feedback

Abu-Baker Ggayi

Work experience
  • October, 2009 - September, 2010
  • Fulltime
  • Project title: Entebbe Mother and Baby Study (EMABS) - This was a randomized placebo controlled trial which initially sought to study the effect of worms and their treatment during pregnancy and early childhood on children’s response to immunization and childhood infections.
  • Responsibilities
  • 1. Clinical care of mothers and their babies
  • 2. collection of exposure and outcome research data
  • 3. Contributed to data cleaning
  • 4. Contributed to manuscript writing
  • 5. Supervised Nurses, field workers and data entry officers

Abu-Baker Ggayi

Work experience
  • March, 2009 - September, 2009
  • Fulltime
  • Medical Officer/field coordinator- - Studies on human papilloma virus infection and cancer of the cervix
  • Responsibilities
  • 1. Performed colposcopy to identify cervical pre-cancerous lesions 2. Performed cervical pap smears
  • 3. Treated pre-cancerous cervical lesions using cryotherapy

Abu-Baker Ggayi

Work experience
  • Medical officer- TASO/MRC/CDC ART Delivery Research Programme (Home-based compared to facility based care models) - A cluster-randomised effectiveness trial
  • Responsibilities
  • 1. Supervised trial support staff, field officers, interviewers and project drivers during data collection.
  • 2. Ensured compliance with the study protocol as well as GCP procedures
  • 3. Performed Verbal autopsy interviews, during field visits to the deceased patients' relatives
  • 4. Actively participated in data cleaning and manuscripts writing

Abu-Baker Ggayi

Education
  • January, 2008 - November, 2010
  • Fulltime

Abu-Baker Ggayi

Work experience
  • Medical Officer & study Team leader(CRYPTO PRO TRIAL) Kalangala Islands
  • Responsibilities/achievements.
  • 1. Sub-investigator providing research and clinical care services
  • 2. Responsible for coordinating all research related activities including Voluntary HIV Counselling and Testing
  • 3. screening, enrollment and follow up activities
  • 4. Co-author on one manuscript ( Wakeham, Katie, et al. "Co-administration of fluconazole increases nevirapine concentrations in HIV-infected Ugandans." Journal of antimicrobial chemotherapy 65.2 (2010): 316-319.
  • 5. Contributed to the writing of the main manuscript

Abu-Baker Ggayi

Education
  • September, 2006 - November, 2007
  • Fulltime

Abu-Baker Ggayi

Work experience
  • Medical officer-Primary prophylaxis with Fluconazole against invasive cryptococcal disease(CRYPTO PRO TRIAL). We screened over 8000 patients and recruited 1519 of them.
  • Responsibilities included:
  • 1. Conducting screening, enrolment procedures on prospective study participants
  • 2. Provided clinical care including history taking, physical examinations and investigations on severely immunocompromised patients
  • 3. Provided in-patient care to critically ill study participants
  • 4. Collected study related and routine data, participated in data cleaning .
  • 5. Participated in manuscript writing for the main paper and a number of sub-studies.

Abu-Baker Ggayi

Work experience
  • November, 2003 - February, 2005
  • Fulltime
  • Responsibilities
  • 1. Overseeing health sub district preventive and curative services including static and outreach immunization services
  • 2. Provision of Primary healthcare services
  • 3. Provided emergency and general medical, obstetric, gynaecological, surgical and paediatric services

Abu-Baker Ggayi

Work experience
  • November, 2002 - October, 2003
  • Fulltime
  • Supervised clinical care (Paediatric and surgical disciplines)

Abu-Baker Ggayi

Education

Abu-Baker Ggayi

Education

Abu-Baker Ggayi

Education
  • January, 1991 - December, 1994
  • Fulltime

Related persons